Joe M. McCord

Joe Milton McCord
Residence Denver, Colorado
Citizenship United States
Fields Biochemistry
Institutions University of Colorado
Alma mater Rhodes College, Duke University
Doctoral advisor Irwin Fridovich
Known for Discovery of superoxide dismutase

Joe Milton McCord (born March 3, 1945) is an American biochemist and current Professor of Medicine at the University of Colorado at Denver. He is most famous for his discovery, along with Irwin Fridovich, of the enzyme superoxide dismutase.[1][2] For this work, Dr. McCord has earned numerous awards and recognition. He has been a member of the board of directors of the LifeVantage Corporation (makers of the dietary supplement Protandim) since 2006.

Contents

Education, Academic Positions, Awards, and Honors

Dr. McCord hold a B.S. in Chemistry from Rhodes College (graduated 1966) and a Ph.D. in Biochemistry from Duke University (graduated 1970), where he also conducted postdoctoral research.

Dr. McCord has previously held biochemistry faculty positions at Duke University Medical Center and University of South Alabama. He currently serves as a professor in the department of Biochemistry, Biophysics, and Molecular Genetics at the University of Colorado Denver.

Dr. McCord has received several awards and honors for his research and discoveries in the field of free radical biochemistry. McCord is a past recipient of the Elliott Cresson Medal, the Discovery Award from the Society for Free Radical Biology and Medicine (SFRBM),[3] and a Lifetime Achievement Award from the Oxygen Society. He holds an Honorary Doctorate from the University of Buenos Aires and has served as Honorary President of the International Society of Antioxidants in Nutrition and Health (ISANH) and as Chairman of the Third International Conference on Superoxide Dismutases at the Institut Pasteur.

LifeVantage/Protandim

Dr. McCord has served on the board of directors (Director of Science) of the LifeVantage Corporation since 2006 [1] and is listed by the SEC as an insider shareholder.[2] LifeVantage is a Utah-based multilevel marketing company that distributes an antioxidant dietary supplement known as Protandim. McCord has co-authored 7 studies on the product[4][5][6][7][8][9][10] and participates in distributor training.[3]

In June 2011, Dr. McCord accepted a position as Chief Scientific Officer for LifeVantage Corporation.

Publications

McCord has published more than 200 articles in numerous scientific journals and books.

Journal Articles

The following is a partial list of Dr. McCord's published articles:

Books

References

  1. ^ McCord, JM; Fridovich, I. (1969). "Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein)". J. Biol. Chem. 244 (22): 6049–55. PMID 5389100. 
  2. ^ Keele, BB Jr; McCord, JM; Fridovich, I. (1971). "Superoxide dismutase from escherichia coli B. A new manganese-containing enzyme.". J. Biol. Chem. 245 (22): 6176–81. PMID 4921969. 
  3. ^ "SFRBM - Society for Free Radical Biology and Medicine". http://www.sfrbm.org. 
  4. ^ Nelsona SK, Bose SK, Grunwald GK, Myhill P, McCord JM (15 January 2006). "The induction of human superoxide dismutase and catalase in vivo: A fundamentally new approach to antioxidant therapy". Free Radical Biology & Medicine 40 (2): 341–347. doi:10.1016/j.freeradbiomed.2005.08.043. PMID 16413416. http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T38-4J1J58D-3&_user=10&_coverDate=01%2F15%2F2006&_rdoc=1&_fmt=high&_orig=search&_sort=d&_docanchor=&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=4c980c4fd7aabff2bd0222038b4c1fb0. 
  5. ^ Velmurugan, Kalpana; Alam, et al.; McCord, JM; Pugazhenthi, S (31 October 2008). "Synergistic induction of heme oxygenase – 1 by the components of the antioxidant supplement Protandim". Free Radical Biology & Medicine 46 (3): 430–40. doi:10.1016/j.freeradbiomed.2008.10.050. PMID 19056485. http://www.lifevantage.com/documents/2009%20FRBM%20Protandim%20synergistically%20activates%20Nrf2.pdf. 
  6. ^ Liu, Jianfeng; et al., X; Robbins, D; Li, G; Shi, R; McCord, JM; Zhao, Y; Bauer, Joseph Alan (22 April 2009). "Protandim, a Fundamentally New Antioxidant Approach in Chemoprevention Using Mouse Two-Stage Skin Carcinogenesis as a Model". PLoS ONE 4(4): e5284 4 (4): e5284. doi:10.1371/journal.pone.0005284. PMC 2668769. PMID 19384424. http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0005284. 
  7. ^ Robbins D, Gu X, Shi R, Liu J, Wang F, Ponville J, McCord JM, Zhao Y (July 30, 2010). "The chemopreventive effects of Protandim: modulation of p53 mitochondrial translocation and apoptosis during skin carcinogenesis". PLoS ONE 5 (7): e11902. doi:10.1371/journal.pone.0011902. PMC 2912769. PMID 20689586. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2912769. 
  8. ^ Bogaard, Harm J.; et al., R; Henderson, SC; Long, CS; Kraskauskas, D; Smithson, L; Ockaili, R; McCord, JM et al. (2 November 2009). "Chronic Pulmonary Artery Pressure Elevation Is Insufficient to Explain Right Heart Failure". Circulation 120 (20): 1951–1960. doi:10.1161/CIRCULATIONAHA.109.883843. PMID 19884466. http://circ.ahajournals.org/cgi/content/abstract/120/20/1951?maxtoshow=&hits=10&RESULTFORMAT=&fulltext=Chronic+Pulmonary+Artery+Pressure+Elevation+Is+Insufficient+to+Explain+Right+Hea&searchid=1&FIRSTINDEX=0&resourcetype=HWCIT. 
  9. ^ Qureshi MM, McClure WC, Arevalo NL, Rabon RE, Mohr B, Bose SK, McCord JM, Tseng BS (2010). "The dietary supplement protandim decreases plasma osteopontin and improves markers of oxidative stress in muscular dystrophy Mdx mice". J Diet Suppl 1 (7): 159–178. doi:10.3109/19390211.2010.482041. PMC 2926985. PMID 20740052. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2926985. 
  10. ^ Joddar B, Reen RK, Firstenberg MS, Varadharaj S, McCord JM, Zweier JL, Gooch KJ (15 December 2010 [Epub ahead of print]). "Protandim attenuates intimal hyperplasia in human saphenous veins cultured ex vivo via a catalase-dependent pathway". Free Radic Biol Med. doi:10.1016/j.freeradbiomed.2010.12.008. PMID 21167278. 

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